 |
The cat is a dilettante in fur. -Unknown |
 |
|
 |
Prescription items are NON-RETURNABLE and NON REFUNDABLE Amoxicillin/Clavulanate Tablets An orally administered formulation comprised of the broad-spectrum antibiotic amoxicillin trihydrate and the ??-lactamase inhibitor, clavulanate potassium (the potassium salt of clavulanic acid). This treatment applies to the following species: Cats Dogs Amoxicillin trihydrate is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative, aerobic and anaerobic microorganisms. It does not resist destruction by ??-lactamases; therefore, it is not effective against ??-lactamase-producing bacteria. Chemically, it is D(-)-??-amino-p-hydroxybenzyl penicillin trihydrate. Clavulanic acid, an inhibitor of ??-lactamase enzymes, is produced by the fermentation of Streptomyces clavuligerus. Clavulanic acid by itself has only weak antibacterial activity. Chemically, clavulanate potassium is potassium z-(3R,5R)-2-??-hydroxyethylidene clavam-3-carboxylate. ACTIONS: Amoxicillin Trihydrate and Clavulanate Potassium Tablets are stable in the presence of gastric acid and are not significantly influenced by gastric or intestinal contents. The 2 components are rapidly absorbed resulting in amoxicillin and clavulanic acid concentrations in serum, urine, and tissues similar to those produced when each is administered alone. Amoxicillin and clavulanic acid diffuse readily into most body tissues and fluids with the exception of brain and spinal fluid, which amoxicillin penetrates adequately when meninges are inflamed. Most of the amoxicillin is excreted unchanged in the urine. Clavulanic acid's penetration into spinal fluid is unknown at this time. Approximately 15% of the administered dose of clavulanic acid is excreted in the urine within the first 6 012KV-38906 365862503206