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The cat is a dilettante in fur. -Unknown |
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Prescription items are NON-RETURNABLE and NON REFUNDABLE Cystorelin Injection expiration date 5/2021. CYSTORELIN (R) is indicated for the treatment of ovarian follicular cysts in dairy cattle. Ovarian cysts are non-ovulated follicles with incomplete luteinization which result in nymphomania or irregular estrus. Historically, cystic ovaries have responded to an exogenous source of luteinizing hormone (LH) such as human chorionic gonadotropin. CYSTORELIN (R) initiates release of endogenous LH to cause ovulation and luteinization. The recommended intravenous or intramuscular dosage of CYSTORELIN (R) is 100 mcg (2 mL) per cow. Ingredients: Each mL of CYSTORELIN (R) contains: Gonadorelin diacetate tetrahydrate 50 mcg Benzyl Alcohol 9 mg Sodium Chloride 7.47 mg Water for Injection, U.S.P. q.s. pH adjusted with potassium phosphate (monobasic and dibasic). Storage: Keep at or below 77??f, a brief excursion to 86??f permitted. Discard Remaining Product 90 Days After First Use. Endogenous gonadorelin is synthesized and/or released from the hypothalamus during various stages of the bovine estrus cycle following appropriate neurogenic stimuli. It passes via the hypophyseal portal vessels, to the anterior pituitary to effect the release of gonadotropins (e.g. LH, FSH). Synthetic gonadorelin administered intravenously or intramuscularly also causes the release of endogenous LH or FSH from the anterior pituitary. Gonadorelin diacetate tetrahydrate has been shown to be safe. The LD50 for mice and rats is greater than 60 mg/kg, and for dogs, greater than 600 mcg/kg, respectively. No untoward effects were noted among rats or dogs administered 120 mcg/kg/day or 72 mcg/kg/day intravenously for 15 days. It has no adverse effects on heart rate, blood pressure, or EKG to unanesthetized dogs at 30mil 012MER01-15 P00900